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The phosphoinositide 3-kinase (PI3K) family is a group of enzymes that generate lipid 'second messengers' that mediate signal transduction. PI3K signaling initiates normal cell processes that are frequently disrupted by carcinogenesis: growth, differentiation (the structure and/or function of a cell is changed), survival, proliferation, migration, metabolism, and metastasis. - Read more   Tweet this Link

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In order for a physician to determine the stage, severity and general prognosis of a patient suffering from mesothelioma, a variety of physical health aspects must be taken into account. Determining prognosis is an extensive and elaborate process that will allow the patient to better understand treating this disease and survival. - Read more   Tweet this Link

The diagnosis of mesothelioma begins with a review of the patient’s medical history and a physical examination. If the examining practitioner suspects a problem, she may order a number of tests including lab work and imaging studies. A combination of MRI, CT, PET, and x-rays may be used to find out the cancer’s location, size, and type. Imaging studies are often followed by biopsies to detect the presence of cancer cells in fluid or tissue. - Read more   Tweet this Link

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